Study Design & Validity

S5E16 Simpson’s Paradox

In this week’s episode Greg and Patrick talk all about Simpson’s Paradox: what it is, examples of where it occurs in real life, and why we might not really need to think about it as a paradox at all.  Along the way they also discuss Apple Vision, The Simpsons  predicting the future, sitting too close […]

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S5E13 The Confidence Interval’s Tale

In this week’s episode Greg and Patrick talk about confidence intervals: symmetric and asymmetric, asymptotic and bootstrapped, how to interpret them, and how not to interpret them. Along they way they also discuss tire pressure gauge mysteries, conference travel reimbursement, phases of the moon, gyroscopic effects, baseball walk-of-shame, why people hate us, settling out of

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S3E16: Your COVID Rapid Test Result: Are You Positive You’re Positive?

In today’s episode, Patrick and Greg use the context of COVID rapid tests to discuss issues of sensitivity, specificity, positive and negative predicted values, and the generally questionable utility of test accuracy information. Along the way they also discuss escape rooms, C4, Embassy Suites, palak paneer, 93% accurate, astragali, SAT prep courses, the volume of

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S3E10: Observation and Exploration

Patrick and Greg discuss the often forgotten importance of observation and exploration for the purpose of suggesting patterns and forming hypotheses, which can later be refined and rigorously tested within the framework of our well-developed confirmatory machinery. Along the they way they also discuss Orlando road trips, our inner child, crappy glue, melted chocolate, leaning

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S3E08: Statistical Degrees of Freedom…An Intimate Stranger

In today’s episode Patrick and Greg talk about statistical degrees of freedom: what they represent, how they are computed, and the importance they play in daily life. Along the way they also mention color blindness, the Skinnylicious menu, Kevin Bacon, Elmo’s Diner, the flatties, Amtrak, drinking Guinness at room temperature, sudoku, courage, paying the reaper,

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S3E07: In Defense of Researcher Degrees of Freedom

In this episode, Greg and Patrick discuss the many places where researchers make decisions throughout the research process, and they weigh the pros and cons of those researchers having such decision-making freedom. Along the way, they also mention Lucky Charms, frozen waffles for dinner, the fifth down, forking paths, Dirty Deeds Done Dirt Cheap, sharks

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S3E04: Two Time Point Data: What Is Your Quest?

Patrick and Greg talk about the potential advantages and disadvantages of alternative approaches to analyzing two time-point data. They discuss traditional models for raw and residualized change scores, and describe how each of these remains baked into the soul of contemporary models for repeated measures data.  Along the way they also mention: 24 inch pizza

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