Study Design & Validity

S2E05: Model Based Thinking

In this episode Greg and Patrick wander semi-drunkenly around the topic of model-based inference and discuss how this perspective can help move us forward as a scientific discipline. They also somehow manage to discuss explosives, sniffing glue, homemade 787s, catfish noodling, the Ikea helpline, Calvinball, Ludwig Beethoven, Rube Goldberg, hell’s half acre, denouements, and intolerable […]

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S2E02: The Auto-Regressive Cross-Lagged Horror Picture Show

Patrick and Greg open with a disagreement about time travel movies, which then somehow devolves into a discussion of alternative approaches to modeling longitudinal data. They agree that a core issue to consider is the separation of within-person and between-person components of change over time, both theoretically and analytically. Throughout the discussion they also mention

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S1E26: The Internal Validity Pre-Flight Checklist

Greg and Patrick talk about internal validity — broadly and traditionally — but also as an increasingly important lens through which to view our information-saturated world, and be responsible, critical, and skeptical members of scientific communities as well as society. Along the way, they also mention gargling bleach, 5G cell towers, vaping lysol, fecal transplants,

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S1E23: Computer Simulation: Carlo. Monte Carlo.

Patrick and Greg spend an hour stumbling through the world of Monte Carlo computer simulation methodology as a way of knowing within the quantitative sciences. They also delve into: bad ideas, the Dans in Patrick’s life, unique Zoom backgrounds, typical birth weights, theoretical models underlying reading glasses, Jan Ken Pon, being due, archery, blue and

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S1E21: Integrative Data Analysis — The Quest for a Cooperative, Cumulative Science

Patrick and Greg are inspired by the community support we are witnessing during this time of crisis, and they expand this discussion into the community of science. They drill down into the collaborative approach of integrative data analysis in which models are fit to data that have been aggregated across multiple independent samples. They also

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S1E17: Planned Missing Designs (or, How to Beat a Metaphor to Death)

Greg and Patrick start with what seems like a reasonable metaphor linking musical compositions to planned missing data designs, and then they proceed to beat it to death. Then, just when you think they’ve buried it, they dig it back up and beat the carcass some more before eventually just running out of time. In

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